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Schizandrin B

CAS No. 61281-37-6

Schizandrin B( Wuweizisu B )

Catalog No. M15307 CAS No. 61281-37-6

Schisandrin B(Wuweizisu-B) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Schizandrin B
  • Note
    Research use only, not for human use.
  • Brief Description
    Schisandrin B(Wuweizisu-B) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae.
  • Description
    Schisandrin B(Wuweizisu-B) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae, has been shown to produce antioxidant effect on rodent liver and heart.
  • In Vitro
    Real Time qPCR Cell Line:lymphocyte Concentration:10-50 μM Incubation Time:4 h Result:Increase in relative mRNA copy number of Nrf2, HO-1, TrxR1, and GCLC.Increased basal ROS levels and decreased GSH/GSSG ratio.
  • In Vivo
    Animal Model:Mice endotoxic shock model Dosage:80 mg/kg.Administration:Intraperitoneally injected (i.p.), single dose.Result:Decreased proliferation and secretion of the proinflammatory cytokines IL-2, IL-6, and IFN-g .
  • Synonyms
    Wuweizisu B
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    ATM/ATR
  • Recptor
    ATR
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    61281-37-6
  • Formula Weight
    400.46
  • Molecular Formula
    C23H28O6
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 10 mg/mL (24.97 mM); DMSO: 80 mg/mL (199.77 mM)
  • SMILES
    COC1=C(OC)C(OC)=C2C(CC(C)C(C)CC3=CC4=C(OCO4)C(OC)=C23)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bunel V, et al. J Appl Toxicol. 2014 Dec;34(12):1311-9.
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