Schizandrin B

CAS No. 61281-37-6

Schizandrin B( Wuweizisu B )

Catalog No. M15307 CAS No. 61281-37-6

Schisandrin B(Wuweizisu-B) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 82 In Stock
5MG 75 In Stock
10MG 123 In Stock
25MG 231 In Stock
50MG 405 In Stock
100MG 569 In Stock
200MG 806 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Schizandrin B
  • Note
    Research use only, not for human use.
  • Brief Description
    Schisandrin B(Wuweizisu-B) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae.
  • Description
    Schisandrin B(Wuweizisu-B) is a dibenzocyclooctadiene derivative isolated from Fructus Schisandrae, has been shown to produce antioxidant effect on rodent liver and heart.
  • In Vitro
    Real Time qPCR Cell Line:lymphocyte Concentration:10-50 μM Incubation Time:4 h Result:Increase in relative mRNA copy number of Nrf2, HO-1, TrxR1, and GCLC.Increased basal ROS levels and decreased GSH/GSSG ratio.
  • In Vivo
    Animal Model:Mice endotoxic shock model Dosage:80 mg/kg.Administration:Intraperitoneally injected (i.p.), single dose.Result:Decreased proliferation and secretion of the proinflammatory cytokines IL-2, IL-6, and IFN-g .
  • Synonyms
    Wuweizisu B
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    ATM/ATR
  • Recptor
    ATR
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    61281-37-6
  • Formula Weight
    400.46
  • Molecular Formula
    C23H28O6
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 10 mg/mL (24.97 mM); DMSO: 80 mg/mL (199.77 mM)
  • SMILES
    COC1=C(OC)C(OC)=C2C(CC(C)C(C)CC3=CC4=C(OCO4)C(OC)=C23)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bunel V, et al. J Appl Toxicol. 2014 Dec;34(12):1311-9.
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