Cart
sales@molnova.com
Home - Products - Autophagy - SIK - rac Pterosin B

rac Pterosin B

CAS No. 60657-37-6

rac Pterosin B( Pterosine B )

Catalog No. M15274 CAS No. 60657-37-6

rac Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    rac Pterosin B
  • Note
    Research use only, not for human use.
  • Brief Description
    rac Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain.
  • Description
    rac Pterosin B is a potent and specific SIK3 signaling inhibitor that suppresses SIK3 downstream cascades by up-regulating the phosphorylation levels in the SIK3 C-terminal regulatory domain; shows no effect on up-regulation of MEF2 and down-regulation of CRTC2 activities by SIK1 or SIK2; promotes glucose production by up-regulating gluconeogenic gene expression in mouse hepatoma AML-12 cells, decreases the glycogen content and stimulates an association between PHKG2 and SIK3.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Pterosine B
  • Pathway
    Autophagy
  • Target
    SIK
  • Recptor
    SIK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    60657-37-6
  • Formula Weight
    218.296
  • Molecular Formula
    C14H18O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1CC2=C(C1=O)C(=C(C(=C2)C)CCO)C
  • Chemical Name
    2,3-Dihydro-6-(2-hydroxyethyl)-2,5,7-trimethyl-1H-inden-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Itoh Y, et al. J Biol Chem. 2015 Jul 17;290(29):17879-93. 2. Yahara Y, et al. Nat Commun. 2016 Mar 24;7:10959.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • YKL-05-099

    YKL-05-099 (YKL 05-099) is a novel potent, selective pan-SIK inhibitor with IC50 of 10, 40 and 30 nM for SIK1, 2 and 3, respectively.

  • WH-4-025

    WH-4-025 is a?Salt-inducible kinase (SIK)?inhibitor.

  • ARN-3236

    ARN-3236 is a novel potent, selective, and orally active SIK2 inhibitor with IC50 of <1 nM.

Sign In Join Free