Tenoxicam( Ro 12-0068 )

Catalog No. M15222 CAS No. 59804-37-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Tenoxicam
Note

Research use only, not for human use.
Brief Description

Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Description

Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.(In Vitro):Tenoxicam (Ro-12-0068) is a non-steroidal anti-inflammatory drug (NSAID).(In Vivo):Tenoxicam (Ro-12-0068) was administered intraperitoneally immediately after BCAO. Histological analyses show that ischemia produced significant striatal as well as hippocampal lesions which were reversed by the Tenoxicam (Ro-12-0068) treatment. Tenoxicam (Ro-12-0068) also significantly reduced, to control levels, the increased myeloperoxidase activity in hippocampus homogenates observed after ischemia.
In Vitro

Tenoxicam (Ro-12-0068) is a non-steroidal anti-inflammatory drug (NSAID).
In Vivo

Tenoxicam (Ro-12-0068) was administered intraperitoneally immediately after BCAO. Histological analyses show that ischemia produced significant striatal as well as hippocampal lesions which were reversed by the Tenoxicam (Ro-12-0068) treatment. Tenoxicam (Ro-12-0068) also significantly reduced, to control levels, the increased myeloperoxidase activity in hippocampus homogenates observed after ischemia.
Synonyms

Ro 12-0068
Pathway

Chromatin/Epigenetic
Target

COX
Recptor

COX
Research Area

Inflammation/Immunology
Indication

——

CAS Number

59804-37-4
Formula Weight

337.37
Molecular Formula

C13H11N3O4S2
Purity

>98% (HPLC)
Solubility

DMSO: 68 mg/mL (201.55 mM)
SMILES

O=C(C1=C(O)C2=C(C=CS2)S(N1C)(=O)=O)NC3=NC=CC=C3
Chemical Name

4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide

1.Yamada M, et al. J Pharmacol Exp Ther. 1997 May;281(2):1005-12.

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