Piperacillin sodium salt

Research use only, not for human use.

Piperacillin is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.

Piperacillin is a semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections.

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Animal Model:BALB/c low inoculum model of K. pneumoniae, KEN-11 strain Dosage:100 mg/kg Administration:Intravenous injection (i.v.), 4 times a day, 5 d, in combination with Tazobactam (12.5 mg/kg, i.v., 4 times a day, 5 d)Result:Enabled all mice survived whereas all control mice died by 5 d, decreased the number of bacteria in lungs compared with control group[. Observed no bacteria in the blood of most mice (except for two mice at the early phase) while bacteria were observed in the blood of control group. Observed few inflammatory cells in the alveoli whereas an influx of numerous inflammatory cells were observed in the control group.

CL 227,193 | T-1220

Microbiology/Virology

Antibiotic

β-Lactamase

Infection

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59703-84-3

539.54

C23H26N5NaO7S

>98% (HPLC)

Ethanol: 100 mg/mL (185.34 mM); Water: 100 mg/mL (185.34 mM); DMSO: 100 mg/mL (185.34 mM)

CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+]

sodium;(2S,5R,6R)-6-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

(-20℃)

With Ice Pack

≥ 2 years