Bethanechol chloride( (±)-Bethanechol | Carbamyl-β-methylcholine chloride | NSC 30783 )

Catalog No. M15188 CAS No. 590-63-6

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HPLC

MSDS

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Product Name

Bethanechol chloride
Note

Research use only, not for human use.
Brief Description

Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors.
Description

Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors.(In Vitro):Bethanechol chloride (0.3-300 μM) significantly reduces ileal pacemaker potentials.(In Vivo):Bethanechol (2-12 mg/kg; i.p.) induces drinking and increases urine output of rats in a dose-dependent fashion.
In Vitro

Bethanechol chloride (0.3-300 μM) significantly reduces ileal pacemaker potentials.
In Vivo

Bethanechol (2-12 mg/kg; i.p.) induces drinking and increases urine output of rats in a dose-dependent fashion. Animal Model:Female rats of the Blue Spruce Farms (Sprague-Dawley) (280-330 g) Dosage:2 mg/kg, 4 mg/kg, 8 mg/kg, 12 mg/kg Administration:Intraperitoneal injection Result:Increased water intake during the first hr in a dose-dependent fashion up to the highest dose administered (12 mg/kg).
Synonyms

(±)-Bethanechol | Carbamyl-β-methylcholine chloride | NSC 30783
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

muscarinic receptor
Research Area

Metabolic Disease
Indication

——

CAS Number

590-63-6
Formula Weight

196.68
Molecular Formula

C7H17N2O2·Cl
Purity

>98% (HPLC)
Solubility

Ethanol: 39 mg/mL (198.29 mM); Water: 39 mg/mL (198.29 mM); DMSO: 39 mg/mL (198.29 mM)
SMILES

CC(OC(N)=O)C[N+](C)(C)C.[Cl-]
Chemical Name

2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium chloride

1.Harbaugh RE, et al. J Neurosurg. 1989 Oct;71(4):481-6.

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