Puromycin dihydrochloride
CAS No. 58-58-2
Puromycin dihydrochloride( CL 13,900 | CL 16,536 | NSC 3055 | PDH )
Catalog No. M15154 CAS No. 58-58-2
Puromycin 2hydrochloride is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 37 | In Stock |
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| 25MG | 67 | In Stock |
|
| 50MG | 113 | In Stock |
|
| 100MG | 183 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePuromycin dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionPuromycin 2hydrochloride is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.
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DescriptionPuromycin 2hydrochloride is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.
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In Vitro——
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In Vivo——
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SynonymsCL 13,900 | CL 16,536 | NSC 3055 | PDH
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA synthesis| 60S ribosome
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number58-58-2
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Formula Weight544.44
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Molecular FormulaC22H31Cl2N7O5
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Purity>98% (HPLC)
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SolubilityWater: 100 mg/mL warmed (183.67 mM); DMSO: 100 mg/mL warmed (183.67 mM)
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SMILESO=C(N[C@@H]1[C@@H](CO)O[C@@H](N2C=NC3=C(N(C)C)N=CN=C23)[C@@H]1O)[C@@H](N)CC4=CC=C(OC)C=C4.[H]Cl.[H]Cl
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Chemical Name(2S)-2-Amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide dihydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Proflavine Hemisulfa...
Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands.
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dUTP trisodium
dUTP trisodium is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.
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HALOFUGINONE LACTATE
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM.?Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activityhalofuginone (HF), a widely studied derivative of febrifugine, inhibits the development of T(H)17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway.?HF binds glutamyl-prolyl-tRNA synthetase (EPRS), inhibiting prolyl-tRNA synthetase activity;?this inhibition is reversed by the addition of exogenous proline or EPRS.
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