Clozapine( HF 1854 )

Catalog No. M15120 CAS No. 5786-21-0

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	37	In Stock
10MG	29	In Stock
25MG	42	In Stock
50MG	60	In Stock
100MG	90	In Stock
200MG	161	In Stock
500MG	296	In Stock
1G	440	In Stock

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Biological Information

Product Name

Clozapine
Note

Research use only, not for human use.
Brief Description

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.
Description

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM; mainly used for schizophrenia.Schizophrenia Approved.
In Vitro

——
In Vivo

——
Synonyms

HF 1854
Pathway

GPCR/G Protein
Target

Dopamine Receptor
Recptor

D2|M1mAChR|α2-adrenoceptor
Research Area

Neurological Disease
Indication

Schizophrenia

Chemical Information

CAS Number

5786-21-0
Formula Weight

326.8233
Molecular Formula

C18H19ClN4
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
Chemical Name

5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Seeman P, et al. ACS Chem Neurosci. 2014 Jan 15;5(1):24-9. 2. Zhukovskaya NL, et al. Neurosci Lett. 2000 Jul 21;288(3):236-40. 3. Moreno JL, et al. Psychopharmacology (Berl). 2013 Jan;225(1):217-26.

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