Erythromycin cyclocarbonate( Davercin )

Catalog No. M14997 CAS No. 55224-05-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Erythromycin cyclocarbonate
Note

Research use only, not for human use.
Brief Description

A derivative of Erythromycin that inhibits protein synthesis of bacteria by binding to the 50S ribosome.
Description

A derivative of Erythromycin that inhibits protein synthesis of bacteria by binding to the 50S ribosome, shows activity against Gram-positive and some Gram-negative microorganisms.
In Vitro

Erythromycin is used in treatment of respiratory, gastrointestinal, and genital tract infections, as well as skin and soft tissue infections. Erythromycin, with its ten chiral centers and two sugar substituents (L-cladinose and D-desosamine), is a good starting point for numerous medicinal chemistry efforts for improvement of its biological profile (better activity, higher stability, and improved bioavailability) since the first generation of macrolides, which had low toxicity and good tolerability, are unstable in acidic media, had low toxicity and good tolerability.
In Vivo

——
Synonyms

Davercin
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

Infection
Indication

——

CAS Number

55224-05-0
Formula Weight

759.921
Molecular Formula

C38H65NO14
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@H]4OC(=O)O[C@]14C
Chemical Name

Erythromycin, cyclic 11,12-carbonate