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Liothyronine sodium

CAS No. 55-06-1

Liothyronine sodium( Liothyronine | T3 | ??L-3,3',5-Triiodothyronine )

Catalog No. M14991 CAS No. 55-06-1

Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Liothyronine sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.
  • Description
    Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.(In Vitro):Liothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine sodium binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium promotes growth, induces differentiation and regualtes metabolic effects.
  • In Vitro
    Liothyronine (T3, 100 nM) sodium stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine sodium binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodiumpromotes growth, induces differentiation and regualtes metabolic effects.
  • In Vivo
    ——
  • Synonyms
    Liothyronine | T3 | ??L-3,3',5-Triiodothyronine
  • Pathway
    Endocrinology/Hormones
  • Target
    THR
  • Recptor
    TRα| TRβ
  • Research Area
    Endocrinology
  • Indication
    ——

Chemical Information

  • CAS Number
    55-06-1
  • Formula Weight
    672.96
  • Molecular Formula
    C15H11I3NNaO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL (148.59 mM)
  • SMILES
    C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)[O-])N)I)I)O.[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Timmer DC, et al. J Endocrinol, 2003, 179(2), 217-225.
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