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SW063058
CAS No. 533876-30-1
SW063058( SW-063058 )
Catalog No. M14896 CAS No. 533876-30-1
SW063058 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSW063058
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NoteResearch use only, not for human use.
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Brief DescriptionSW063058 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
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DescriptionSW063058 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
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In Vitro——
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In Vivo——
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SynonymsSW-063058
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PathwayAngiogenesis
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TargetBcl-2
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RecptorBcl-2
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Research Area——
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Indication——
Chemical Information
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CAS Number533876-30-1
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Formula Weight565.181
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Molecular FormulaC22H15BrFIN2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC1C(=O)NC2=C(C=C(C=C2)Br)C(N1C(=O)C3=CC=CC=C3I)C4=CC=C(C=C4)F
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Chemical Name7-bromo-5-(4-fluorophenyl)-4-(2-iodobenzoyl)-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chiang WC, et al. ACS Chem Biol. 2018 Jun 21. doi: 10.1021/acschembio.8b00421.
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