Trimipramine maleate
CAS No. 521-78-8
Trimipramine maleate( —— )
Catalog No. M14837 CAS No. 521-78-8
Tricyclic antidepressant similar to IMIPRAMINE, but with more antihistaminic and sedative properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 50MG | 31 | In Stock |
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| 100MG | 44 | In Stock |
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| 200MG | 63 | In Stock |
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| 500MG | 104 | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTrimipramine maleate
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NoteResearch use only, not for human use.
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Brief DescriptionTricyclic antidepressant similar to IMIPRAMINE, but with more antihistaminic and sedative properties.
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DescriptionTricyclic antidepressant similar to IMIPRAMINE, but with more antihistaminic and sedative properties.
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In Vitro——
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In VivoAnimal Model:Male Wistar rats (220-250 g); implanted osmotic minipump subcutaneously in the dorsal thoracic interscapular regionDosage:5 mg/kg/day Administration:Delivered by smotic minipump; 14 days Result:Decreased the number of frontal cortex 5-HT2 and striatal DA D2 receptors, thus blocked the uptake of 5-HT and dopamine (DA).
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Synonyms——
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT| Sert (Sodium-dependent)| Adrenergic Receptor| DA transporter| Dopamine| H1 receptor| Noradrenaline transporter (Sodium-dependent)
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number521-78-8
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Formula Weight410.51
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Molecular FormulaC24H30N2O4
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESCC(CN1C2=CC=CC=C2CCC3=CC=CC=C31)CN(C)C.C(=C\C(=O)O)\C(=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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SB-399885
SB-399885 is a potent, selective, brain penetrant 5-HT6 receptor antagonist with pKi of 9.11 and 9.02 for human recombinant and native 5-HT6 receptors.
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Homoeriodictyol
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotonin release in differentiated Caco-2 cells.In contrast to other polyphenols, the flavanon Homoeriodictyol promotes glucose uptake by 29.0 ± 3.83% at a concentration of 100 μM.
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cis-Urocanic acid
cis-Urocanic acid is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
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