KX1-004
CAS No. 518058-84-9
KX1-004( KX1004 | KX 1004 | KX1-004 )
Catalog No. M14808 CAS No. 518058-84-9
KX1-004 is a potent small molecule inhibitor of Src-PTK as a potential protective drug for NIHL.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
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| 2MG | 51 | In Stock |
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| 5MG | 85 | In Stock |
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| 10MG | 155 | In Stock |
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| 25MG | 282 | In Stock |
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| 50MG | 456 | In Stock |
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| 100MG | 642 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 1349 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameKX1-004
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NoteResearch use only, not for human use.
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Brief DescriptionKX1-004 is a potent small molecule inhibitor of Src-PTK as a potential protective drug for NIHL.
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DescriptionKX1-004 is a potent small molecule inhibitor of Src-PTK as a potential protective drug for NIHL.
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In Vitro——
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In VivoKX1-004 (30 μM) provides significant protection against noise-induced temporary threshold shift (TTS), permanent threshold shift (PTS) and outer hair cells (OHC) loss.KX1-004 (50 mg/kg) is effective against noise exposure.
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SynonymsKX1004 | KX 1004 | KX1-004
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PathwayTyrosine Kinase
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TargetSrc
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RecptorSrc-PTK
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number518058-84-9
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Formula Weight284.29
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Molecular FormulaC16H13FN2O2
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESO=C(C(N1)=CC2=C1C=CC(F)=C2)NCC3=CC=CC(O)=C3
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Chemical Name5-fluoro-N-(3-hydroxybenzyl)-1H-indole-2-carboxamide.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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1-Naphthyl PP1 hydro...
1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src.
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Lyn peptide inhibito...
Cell-permeable inhibitor of Lyn-dependent effects of the IL-5 receptor. Blocks binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors, blocking Lyn activation. Inhibits IL-5 receptor-mediated eosinophil differentiation and survival in vitro. Inhibits airway eosinophilic inflammation in mouse model of asthma.
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Secretin, canine
Secretin is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Canine secretin can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.
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