Atropine

CAS No. 51-55-8

Atropine( DL-Hyoscyamine | Tropine tropate )

Catalog No. M14792 CAS No. 51-55-8

Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Atropine
  • Note
    Research use only, not for human use.
  • Brief Description
    Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery.
  • Description
    Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery.(In Vitro):Atropine (Tropine tropate; 1 μM; pulmonary veins and arteries) inhibits ACh-induced relaxations in human pulmonary veins.(In Vivo):Atropine (Tropine tropate; 10 mg/kg; i.p.; once, for 40 minutes; Peromyscus sp.) inhibits the cardiac arrhythmia which normally occurs throughout torpor.
  • In Vitro
    Atropine (Tropine tropate; 1 μM; pulmonary veins and arteries) inhibits ACh-induced relaxations in human pulmonary veins.
  • In Vivo
    Atropine (Tropine tropate; 10 mg/kg; i.p.; once, for 40 minutes; Peromyscus sp.) inhibits the cardiac arrhythmia which normally occurs throughout torpor. Animal Model:White-footed mice (Peromyscus sp.)Dosage:10 mg/kg Administration:Intraperitoneal injection; once, for 40 minutes Result:Increased heart rate was a decrease in cardiac arrhythmia.
  • Synonyms
    DL-Hyoscyamine | Tropine tropate
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    mAChR
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    51-55-8
  • Formula Weight
    289.37
  • Molecular Formula
    C17H23NO3
  • Purity
    >98% (HPLC)
  • Solubility
    soluble in Water
  • SMILES
    CN1C2CCC1CC(C2)OC(=O)C(CO)C1=CC=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Huang XP, et al. J Pharmacol Exp Ther. 1998 Sep; 286(3):1129-39.
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