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L-Mimosine
CAS No. 500-44-7
L-Mimosine( Leucenol | NSC 69188 )
Catalog No. M14680 CAS No. 500-44-7
L-Mimosine is a non-protein amino acid, and acts as an iron chelator.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 46 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameL-Mimosine
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NoteResearch use only, not for human use.
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Brief DescriptionL-Mimosine is a non-protein amino acid, and acts as an iron chelator.
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DescriptionL-Mimosine is a non-protein amino acid, and acts as an iron chelator.
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In VitroMimosine, a known chelator of Fe(III), may facilitate Fe(III) uptake in leucaena by serving as a phytosiderophore. Mimosine, a bidentate iron-binding ligand, may also play a role in cellular translocation of iron within leucaena.Mimosine is a toxic nonprotein amino acid that is a major constituent of the tropical legumesLeucaenaandMimosa.Mimosine (400 μM), through iron chelation, reversibly blocks cell cycle progression in MDA-MB-453 human breast cancer cells.Mimosine (400 μM) reduces DNA synthesis by greater than 90% of control within 4 hr of treatment, and suppresses total proline-directed protein kinase activity to less than 10% of control after 16 hr treatment.
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In VivoMimosine (30, and 60 mg/kg) decreases sperm concentration. Animal Model:ICR male mice (6-8 weeks)Dosage:15, 30, or 60 mg/kg Administration:Injected (i.p.) for 7 consecutive days Result:Could significantly reduce sperm concentration as compared to the control or low dose mimosine group (15 mg/kg) at doses of 30 and 60 mg/kg.
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SynonymsLeucenol | NSC 69188
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number500-44-7
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Formula Weight198.18
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Molecular FormulaC8H10N2O4
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Purity>98% (HPLC)
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SolubilityDMSO:0.01 mg/mL (0.05 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)
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SMILESO=C(O)[C@@](N)(N(C=C1)C=CC1=O)CO
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Chemical Name(S)-alpha-Amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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