Forsythin

CAS No. 487-41-2

Forsythin( —— )

Catalog No. M14639 CAS No. 487-41-2

Extracted from Forsythia suspensa;Suitability:The mixed solvent of chloroform and methanol,DMSO;Store the product in sealed,cool and dry condition.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 58 In Stock
25MG 116 In Stock
50MG 169 In Stock
100MG 255 In Stock
500MG 619 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Forsythin
  • Note
    Research use only, not for human use.
  • Brief Description
    Extracted from Forsythia suspensa;Suitability:The mixed solvent of chloroform and methanol,DMSO;Store the product in sealed,cool and dry condition.
  • Description
    Extracted from Forsythia suspensa;Suitability:The mixed solvent of chloroform and methanol,DMSO;Store the product in sealed,cool and dry condition.(In Vitro):Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells.Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes.
  • In Vitro
    Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells.Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes. RT-PCR Cell Line:Human HepG2 hepatocyte cells Concentration:1 μM; 2.5 μM; 5 μM Incubation Time:24 hours Result:Reduced FAS and SREBP-1c mRNA expression.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    p38 MAPK
  • Recptor
    p38 MAPK
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    487-41-2
  • Formula Weight
    534.56
  • Molecular Formula
    C27H34O11
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: Soluble
  • SMILES
    COC1=C(OC)C=C(C=C1)C1OCC2C1COC2C1=C(OC)C=C(OC2OC(CO)C(O)C(O)C2O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pan X, et al. Inflamm Res. 2014 Jul;63(7):597-608.
molnova catalog
related products
  • HPK1-IN-7

    HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM).

  • Dehydrocorydaline ch...

    Dehydrocorydaline chloride is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.

  • OVA-E1 peptide TFA

    OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.