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Forsythin
CAS No. 487-41-2
Forsythin( —— )
Catalog No. M14639 CAS No. 487-41-2
Extracted from Forsythia suspensa;Suitability:The mixed solvent of chloroform and methanol,DMSO;Store the product in sealed,cool and dry condition.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 44 | In Stock |
|
| 5MG | 37 | In Stock |
|
| 10MG | 61 | In Stock |
|
| 25MG | 123 | In Stock |
|
| 50MG | 175 | In Stock |
|
| 100MG | 263 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 640 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameForsythin
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NoteResearch use only, not for human use.
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Brief DescriptionExtracted from Forsythia suspensa;Suitability:The mixed solvent of chloroform and methanol,DMSO;Store the product in sealed,cool and dry condition.
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DescriptionExtracted from Forsythia suspensa;Suitability:The mixed solvent of chloroform and methanol,DMSO;Store the product in sealed,cool and dry condition.(In Vitro):Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells.Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes.
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In VitroPhillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells.Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes. RT-PCR Cell Line:Human HepG2 hepatocyte cells Concentration:1 μM; 2.5 μM; 5 μM Incubation Time:24 hours Result:Reduced FAS and SREBP-1c mRNA expression.
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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Targetp38 MAPK
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Recptorp38 MAPK
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Research AreaMetabolic Disease
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Indication——
Chemical Information
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CAS Number487-41-2
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Formula Weight534.56
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Molecular FormulaC27H34O11
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Purity>98% (HPLC)
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SolubilityDMSO: Soluble
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SMILESCOC1=C(OC)C=C(C=C1)C1OCC2C1COC2C1=C(OC)C=C(OC2OC(CO)C(O)C(O)C2O)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pan X, et al. Inflamm Res. 2014 Jul;63(7):597-608.
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