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RG108
CAS No. 48208-26-0
RG108( N-Phthalyl-L-Tryptophan )
Catalog No. M14614 CAS No. 48208-26-0
RG108 is an inhibitor of DNA methyltransferase with IC50 of 115 nM in a cell-free assay, does not cause trapping of covalent enzymes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 57 | In Stock |
|
| 25MG | 107 | In Stock |
|
| 50MG | 194 | In Stock |
|
| 100MG | 272 | In Stock |
|
| 200MG | 381 | In Stock |
|
| 500MG | 618 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRG108
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NoteResearch use only, not for human use.
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Brief DescriptionRG108 is an inhibitor of DNA methyltransferase with IC50 of 115 nM in a cell-free assay, does not cause trapping of covalent enzymes.
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DescriptionRG108 is an inhibitor of DNA methyltransferase with IC50 of 115 nM in a cell-free assay, does not cause trapping of covalent enzymes.
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In Vitro——
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In Vivo——
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SynonymsN-Phthalyl-L-Tryptophan
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PathwayChromatin/Epigenetic
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TargetDNMT
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RecptorDNA methyltransferase (DNMT)
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number48208-26-0
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Formula Weight334.33
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Molecular FormulaC19H14N2O4
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Purity>98% (HPLC)
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SolubilityEthanol: 67 mg/mL (200.4 mM); DMSO: 67 mg/mL (200.4 mM)
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SMILESO=C(O)[C@H](CC1=CNC2=CC=CC=C12)N3C(C4=CC=CC=C4C3=O)=O
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Chemical Name(S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Brueckner B, et al, Y Res, 2005, 65(14), 6305-631
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