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Anguizole
CAS No. 442666-98-0
Anguizole( Anguizole )
Catalog No. M14509 CAS No. 442666-98-0
Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 789 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAnguizole
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NoteResearch use only, not for human use.
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Brief DescriptionAnguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2).
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DescriptionAnguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM; disrupts NS4B-AH2-mediated biological functions of NS4B, NS4B's dimerization/multimerization, its proper subcellular localization, as well as its interaction with NS5A.
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In Vitro——
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In Vivo——
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SynonymsAnguizole
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PathwayMicrobiology/Virology
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TargetHCV
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RecptorHCV
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number442666-98-0
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Formula Weight408.8078
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Molecular FormulaC17H11ClF2N4O2S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(C1=NN2C(C(F)(Cl)F)=CC(C3=CC=CO3)=NC2=C1)NCC4=CC=CS4
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Chemical NamePyrazolo[1,5-a]pyrimidine-2-carboxamide, 7-(chlorodifluoromethyl)-5-(2-furanyl)-N-(2-thienylmethyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Choi M, et al. Virus Genes. 2013 Dec;47(3):395-407.
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