Cart
sales@molnova.com
Pyrantel tartrate
CAS No. 33401-94-4
Pyrantel tartrate( —— )
Catalog No. M14131 CAS No. 33401-94-4
Pyrantel tartrate is an antinematodal thiophene; and can elicit spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors on body wall muscle.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 32 | In Stock |
|
| 500MG | 56 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePyrantel tartrate
-
NoteResearch use only, not for human use.
-
Brief DescriptionPyrantel tartrate is an antinematodal thiophene; and can elicit spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors on body wall muscle.
-
DescriptionPyrantel tartrate is an antinematodal thiophene; and can elicit spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors on body wall muscle.(In Vitro):Pyrantel tartrate (10 nM-10 μM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity.(In Vivo):Pyrantel tartrate (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%.
-
In VitroPyrantel tartrate (10 nM-10 μM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity. Cell Viability AssayCell Line:A. suum Concentration:10 nM-10 μM Incubation Time:72 h Result:Inhibited A. suum with a pEC50 value of 7.24.Cell Viability Assay Cell Line:N. americanus Concentration:0-168.2 M (0-100 μg/mL)Incubation Time:72 h Result:Inhibited third-stage larvae and adult of N. americanus with IC50 values of 2.0 and 7.6 mg/mL, respectively.
-
In VivoPyrantel tartrate (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%. Animal Model:Male Syrian Golden hamsters (3-week-old; A. ceylanicum-infected).Dosage:10 mg/kg Administration:Oral administration; single.Result:Exhibited worm burden reduction and worm expulsion rates of 87.2% and 63.4%, respectively.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research AreaInfection
-
Indication——
Chemical Information
-
CAS Number33401-94-4
-
Formula Weight356.39
-
Molecular FormulaC15H20N2O6S
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM
-
SMILESCN1CCCN=C1/C=C/C2=CC=CS2.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Pratt SE, et al. Am J Vet Res. 1981 May;42(5):871-2.
molnova catalog
related products
-
Xylohexaose
Xylohexaose is a xylooligosaccharide consisting of six xylose residues. Xylohexaose can be used as substrate in the xylan hydrolysis properties assay.
-
(Ser8)-GLP-1 (7-36) ...
(Ser8)-GLP-1 (7-36) amide, human is a glucagon-like peptide 1 amide derived from glucagonogen, a cleavage product of the GLP-1 (1-36) amide peptide. (Ser8)-GLP-1 (7-36) amide, human is an entero-insulinotropic hormone that causes glucose-dependent release of insulin from pancreatic β-cells and affects gastrointestinal motility and secretion.
-
3,5-Diiodo-L-thyroni...
3, 5-Diiodo-L-thyronine is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance.
