Buspirone hydrochloride

CAS No. 33386-08-2

Buspirone hydrochloride( MJ9022-1 )

Catalog No. M14129 CAS No. 33386-08-2

Buspirone hydrochloride is an anxiolytic psychotropic drug, is used to treat generalized anxiety disorder (GAD).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
25MG 29 In Stock
50MG 34 In Stock
100MG 47 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Buspirone hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Buspirone hydrochloride is an anxiolytic psychotropic drug, is used to treat generalized anxiety disorder (GAD).
  • Description
    Buspirone hydrochloride is an anxiolytic psychotropic drug, is used to treat generalized anxiety disorder (GAD).(In Vitro):Buspirone hydrochloride (0-400 μg/mL; 6 hours) has cytotoxic effect in Lymphocytes. Buspirone hydrochloride (0-180 μg/mL; 0-3 hours; Lymphocytes) induces ROS formation, MMP collapse, lipid peroxidation, lysosomal damage and elevation of glutathione disulfide (GSSG).(In Vivo):Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) reduces anxiety/depression behaviors.Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) restores IS-shifted β-diversity in the gut microbiota.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MJ9022-1
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT| Dopamine
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    33386-08-2
  • Formula Weight
    421.96
  • Molecular Formula
    C21H32ClN5O2
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 36 mg/mL (85.31 mM); Water: 84 mg/mL (199.07 mM); DMSO: 84 mg/mL (199.07 mM)
  • SMILES
    Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)C1=NC=CC=N1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.VanderMaelen CP, et al. Eur J Pharmacol, 1986, 129(1-2), 123-130.
molnova catalog
related products
  • Pizotifen

    Pizotifen(Pizotyline) is a highly selective 5-HT receptor blocking agent, which is a benzocycloheptane based drug.

  • XEN-445

    XEN445, a potent and selective endothelial lipase(EL) inhibitor (IC50=0.237 uM), exhibitis good ADME and PK properties.

  • XL888

    XL888 is an ATP-competitive inhibitor of Hsp90 ( IC50: 24 nM). Heat shock protein 90 (Hsp90) is a chaperone that maintains the functionality of client proteins involved in cell proliferation, cell cycling, and apoptosis.