Hemicholinium dibromide
CAS No. 312-45-8
Hemicholinium dibromide( HC3 | HC 3 | HC-3 | Hemicholinium3 | Hemicholinium 3 )
Catalog No. M13999 CAS No. 312-45-8
A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 73 | In Stock |
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| 5MG | 39 | In Stock |
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| 10MG | 63 | In Stock |
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| 25MG | 141 | In Stock |
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| 50MG | 202 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameHemicholinium dibromide
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NoteResearch use only, not for human use.
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Brief DescriptionA potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system.
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DescriptionA potent inhibitor of the high affinity uptake system for choline. It has less effect on the low affinity uptake system. Since choline is one of the components of acetylcholine, treatment with hemicholinium can deplete acetylcholine from cholinergic terminals. Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.
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In VitroCell Viability Assay Cell Line:The human small cell lung carcinoma cell line NCI-H69 Concentration:1 mM Incubation Time:Added every day for 2 days. Result:Markedly inhibited cell viability.
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In Vivo——
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SynonymsHC3 | HC 3 | HC-3 | Hemicholinium3 | Hemicholinium 3
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PathwayOthers
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TargetOther Targets
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RecptorChR
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Research Area——
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Indication——
Chemical Information
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CAS Number312-45-8
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Formula Weight574.35
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Molecular FormulaC24H34Br2N2O4
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESOC1(C2=CC=C(C3=CC=C(C4(O)OCC[N+](C)(C)C4)C=C3)C=C2)OCC[N+](C)(C)C1.[Br-].[Br-]
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Chemical Name2,2'-([1,1'-biphenyl]-4,4'-diyl)bis(2-hydroxy-4,4-dimethylmorpholin-4-ium) bromide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Soukup O, et al. Toxicol Lett. 2012 Aug 3;212(3):315-9.
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