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Ciluprevir
CAS No. 300832-84-2
Ciluprevir( BILN2061 | BILN 2061 )
Catalog No. M13936 CAS No. 300832-84-2
Ciluprevir (BILN2061) is a potent HCV NS3/4A protease inhibitor with Ki of 0.66 and 0.30 nM for NS3-NS4A protease of HCV 1b and HCV 1a, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1593 | Get Quote |
|
| 50MG | 3222 | Get Quote |
|
| 100MG | 4410 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCiluprevir
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NoteResearch use only, not for human use.
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Brief DescriptionCiluprevir (BILN2061) is a potent HCV NS3/4A protease inhibitor with Ki of 0.66 and 0.30 nM for NS3-NS4A protease of HCV 1b and HCV 1a, respectively.
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DescriptionCiluprevir (BILN2061) is a potent HCV NS3/4A protease inhibitor with Ki of 0.66 and 0.30 nM for NS3-NS4A protease of HCV 1b and HCV 1a, respectively; inhibits the replication of HCV replicon 1b and 1a with IC50 of 3 nM and 4 nM, respectively.HCV Infection Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsBILN2061 | BILN 2061
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PathwayMicrobiology/Virology
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TargetHCV
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RecptorHCV
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Research AreaInfection
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IndicationHCV Infection
Chemical Information
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CAS Number300832-84-2
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Formula Weight774.934
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Molecular FormulaC40H50N6O8S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C([C@]([C@]1([H])/C=C\CCCCC[C@@H]2NC(OC3CCCC3)=O)(C1)NC([C@@](C[C@@H](OC4=CC(C5=CSC(NC(C)C)=N5)=NC6=CC(OC)=CC=C46)C7)([H])N7C2=O)=O)O
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Chemical Name(2R,6S,13aS,14aR,16aS,Z)-6-(((cyclopentyloxy)carbonyl)amino)-2-((2-(2-(isopropylamino)thiazol-4-yl)-7-methoxyquinolin-4-yl)oxy)-5,16-dioxo-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-car
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lamarre D, et al. Nature. 2003 Nov 13;426(6963):186-9.
2. Lin C, et al. J Biol Chem. 2004 Apr 23;279(17):17508-14.
3. Llinàs-Brunet M, et al. J Med Chem. 2004 Mar 25;47(7):1605-8.
4. Thibeault D, et al. J Virol. 2004 Jul;78(14):7352-9.
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