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CGK-1026
CAS No. 287383-59-9
CGK-1026( CGK 1026 | CGK1026 )
Catalog No. M13877 CAS No. 287383-59-9
A small molecule that inhibits human telomerase reverse transcriptase (hTERT) expression.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 68 | In Stock |
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| 5MG | 62 | In Stock |
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| 10MG | 93 | In Stock |
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| 25MG | 204 | In Stock |
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| 50MG | 369 | In Stock |
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| 100MG | 555 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 1172 | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCGK-1026
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule that inhibits human telomerase reverse transcriptase (hTERT) expression.
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DescriptionA small molecule that inhibits human telomerase reverse transcriptase (hTERT) expression; inhibits the recruitment of HDAC into E2F-pocket protein complexes assembled on the hTERT promoter, inhibits HDAC activity with IC50 of 100 nM; induces G1 arrest of IMR90 cells.
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In Vitro——
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In Vivo——
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SynonymsCGK 1026 | CGK1026
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number287383-59-9
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Formula Weight326.352
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Molecular FormulaC18H18N2O4
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Purity>98% (HPLC)
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SolubilityDMSO: 32.6 mg/mL (100 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C(NO)CCCCCN(C(C1=CC=CC2=CC=CC3=C12)=O)C3=O
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Chemical NameN-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Won J, et al. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11328-33.
2. Alimirah F, et al. Mol Cancer Res. 2007 Mar;5(3):251-9.
3. Song LL, et al. PLoS One. 2010 Jan 5;5(1):e8569.
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