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JTE907
CAS No. 282089-49-0
JTE907( JTE-907 | JTE 907 )
Catalog No. M13857 CAS No. 282089-49-0
A potent, selective, orally active cannabinoid CB2 receptor inverse agonist with Ki of 35.9, 1.55 and 0.38 nM for human, mouse and rat CB2, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 145 | In Stock |
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| 5MG | 122 | In Stock |
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| 10MG | 187 | In Stock |
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| 25MG | 330 | In Stock |
|
| 50MG | 480 | In Stock |
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| 100MG | 684 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameJTE907
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, orally active cannabinoid CB2 receptor inverse agonist with Ki of 35.9, 1.55 and 0.38 nM for human, mouse and rat CB2, respectively.
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DescriptionA potent, selective, orally active cannabinoid CB2 receptor inverse agonist with Ki of 35.9, 1.55 and 0.38 nM for human, mouse and rat CB2, respectively; increases of forskolin-stimulated cAMP production in CHO cells expressing CB2 in vitro, inhibits carrageenin-induced mouse paw edema dose dependently in mice.
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In Vitro——
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In Vivo——
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SynonymsJTE-907 | JTE 907
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCannabinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number282089-49-0
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Formula Weight438.48
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Molecular FormulaC24H26N2O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (285.08 mM)
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SMILESO=C(C1=CC2=C(NC1=O)C(OCCCCC)=C(OC)C=C2)NCC3=CC=C(OCO4)C4=C3
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Chemical NameN-(1,3-Benzodioxol-5-ylmethyl)-1,2-dihydro-7-methoxy-2-oxo-8-(pentyloxy)-3-quinolinecarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Iwamura H, et al. J Pharmacol Exp Ther. 2001 Feb;296(2):420-5.
2. Ueda Y, et al. Eur J Pharmacol. 2005 Sep 27;520(1-3):164-71.
3. Maekawa T, et al. Eur J Pharmacol. 2006 Aug 7;542(1-3):179-83.
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