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AICAR
CAS No. 2627-69-2
AICAR( Acadesine | AICA Riboside )
Catalog No. M13802 CAS No. 2627-69-2
AICAR (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 25MG | 29 | In Stock |
|
| 50MG | 39 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAICAR
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NoteResearch use only, not for human use.
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Brief DescriptionAICAR (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes.
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DescriptionAICAR (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes; inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes at 0.5 mM, inhibits insulin-stimulated glucose and reduces GLUT4 translocation in 3T3-L1 adipocytes; down-regulates the insulin receptor expression in HepG2 cells.
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In Vitro——
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In Vivo——
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SynonymsAcadesine | AICA Riboside
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PathwayMembrane Transporter/Ion Channel
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TargetAMPK
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RecptorAMPK
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Research AreaMetabolic Disease
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Indication——
Chemical Information
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CAS Number2627-69-2
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Formula Weight258.2
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Molecular FormulaC9H14N4O5
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 30 mg/mL
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SMILESO=C(C1=C(N)N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=N1)N
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Chemical Name1H-Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sullivan JE, et al. FEBS Lett. 1994 Oct 10;353(1):33-6.
2. Young ME, et al. FEBS Lett. 1996 Mar 11;382(1-2):43-7.
3. Samari HR, et al. J Biol Chem. 1998 Sep 11;273(37):23758-63.
4. Ayasolla KR, et al. J Neuroinflammation. 2005 Sep 20;2:21.
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