Cart
sales@molnova.com
Home - Products - Apoptosis - Caspase - Emricasan

Emricasan

CAS No. 254750-02-2

Emricasan( IDN-6556 | PF-03491390 )

Catalog No. M13761 CAS No. 254750-02-2

Emricasan (IDN-6556;PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 48 In Stock
5MG 78 In Stock
10MG 132 In Stock
25MG 240 In Stock
50MG 397 In Stock
100MG 584 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Emricasan
  • Note
    Research use only, not for human use.
  • Brief Description
    Emricasan (IDN-6556;PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.
  • Description
    Emricasan (IDN-6556;PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.Steatohepatitis Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    IDN-6556 | PF-03491390
  • Pathway
    Apoptosis
  • Target
    Caspase
  • Recptor
    Caspase
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    254750-02-2
  • Formula Weight
    569.51
  • Molecular Formula
    C26H27F4N3O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 93 mg/mL (163.3 mM); Ethanol: 93 mg/mL (163.3 mM); Water: <1 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    O=C(O)C[C@H](NC([C@H](C)NC(C(NC1=CC=CC=C1C(C)(C)C)=O)=O)=O)C(COC2=C(F)C(F)=CC(F)=C2F)=O
  • Chemical Name
    (3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Xu M, et al. Nat Med. 2016 Oct;22(10):1101-1107. 2. Brumatti G, et al. Sci Transl Med. 2016 May 18;8(339):339ra69. 3. McCall MD, et al. Transplantation. 2012 Jul 15;94(1):30-5.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • BOC-D-FMK

    BOC-D-FMK is a cell-permeable, irreversible, broad spectrum caspase inhibitor, inhibits apoptosis stimulated by TNF-α with IC50 of 39 uM.

  • VX-765

    VX-765 (Belnacasan) is an orally absorbed prodrug of VRT-043198, which is a potent and selective inhibitor of interleukin-converting enzyme/caspase-1 with Ki of 0.8 nM.

  • Cystamine

    Cystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM. Cystamine can be used in studies about Huntington's diseases.

Sign In Join Free