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Catharanthine
CAS No. 2468-21-5
Catharanthine( (+)-3,4-Didehydrocoronaridine )
Catalog No. M13718 CAS No. 2468-21-5
Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 50MG | 36 | In Stock |
|
| 100MG | 53 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCatharanthine
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NoteResearch use only, not for human use.
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Brief DescriptionCatharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.
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DescriptionCatharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.
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In Vitro——
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In VivoAnimal Model:13-week-old male SpragueDawley rats (300-350 g) Dosage:0.5-20 mg/kg Administration:IV; single dose Result:Evoked rapid, transient reductions in BP and HR (lasting ,2 minutes) at low doses (0.5–5 mg/kg), whereas at higher doses (10 and 20 mg/kg), the BP and HR reductions were sustained.
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Synonyms(+)-3,4-Didehydrocoronaridine
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptornAChR
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number2468-21-5
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Formula Weight336.42
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Molecular FormulaC21H24N2O2
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Purity>98% (HPLC)
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SolubilityEthanol: 3 mg/mL (8.91 mM); DMSO: 67 mg/mL (199.14 mM)
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SMILESCCC1=C[C@H]2C[C@]3([C@@H]1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pereira DM, et al. Phytomedicine, 2010, 17(8-9), 646-652.
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