Econazole nitrate

CAS No. 24169-02-6

Econazole nitrate( NSC 243115 | SQ 13,020 )

Catalog No. M13699 CAS No. 24169-02-6

Econazole nitrate (Spectazole) is an imidazole class antifungal medication.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Econazole nitrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Econazole nitrate (Spectazole) is an imidazole class antifungal medication.
  • Description
    Econazole nitrate (Spectazole) is an imidazole class antifungal medication.(In Vitro):Econazole nitrate is an antifungal medication of the imidazole class. It is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. In each of these tests the activity of econazole was compared with that of different reference drugs. Vaginal candidiasis in rats was cured after oral administration of econazole. Toxicity and teratogenicity studies in different laboratory animals indicate that econazole is well tolerated.
  • In Vitro
    Econazole nitrate is an antifungal medication of the imidazole class. It is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. In each of these tests the activity of econazole was compared with that of different reference drugs. Vaginal candidiasis in rats was cured after oral administration of econazole. Toxicity and teratogenicity studies in different laboratory animals indicate that econazole is well tolerated.
  • In Vivo
    ——
  • Synonyms
    NSC 243115 | SQ 13,020
  • Pathway
    Microbiology/Virology
  • Target
    Antifection
  • Recptor
    14-α Demethylase
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    24169-02-6
  • Formula Weight
    444.7
  • Molecular Formula
    C18H15Cl3N2O·HNO3
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 5 mg/mL (11.24 mM); DMSO: 89 mg/mL (200.13 mM)
  • SMILES
    O[N+]([O-])=O.ClC1=CC=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ge S, et al. Int J Pharm. 2014 Apr 25; 465(1-2):120-3
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