Aspartame( L-Aspartyl-L-Phenylalanine methyl ester )

Catalog No. M13628 CAS No. 22839-47-0

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Aspartame
Note

Research use only, not for human use.
Brief Description

Aspartame is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages.
Description

Aspartame is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages.(In Vitro):Aspartame is composed of phenylalanine (an important role in neurotransmitter regulation), aspartic acid (an excitatory neurotransmitter in the central nervous system) and methanol.(In Vivo):Aspartame (4000 mg/kg bw/day; p.o.) shows no adverse effect in acute, subacute and chronic toxicity studies with aspartame, and its decomposition products, conducted in mice, rats, hamsters and dogs.
In Vitro

Aspartame is composed of phenylalanine (an important role in neurotransmitter regulation), aspartic acid (an excitatory neurotransmitter in the central nervous system) and methanol.
In Vivo

Aspartame (4000 mg/kg bw/day; p.o.) shows no adverse effect in acute, subacute and chronic toxicity studies with aspartame, and its decomposition products, conducted in mice, rats, hamsters and dogs.
Synonyms

L-Aspartyl-L-Phenylalanine methyl ester
Pathway

Others
Target

Other Targets
Recptor

Taste receptor| Transient receptor potential cation channel
Research Area

Other Indications
Indication

——

CAS Number

22839-47-0
Formula Weight

294.3
Molecular Formula

C14H18N2O5
Purity

>98% (HPLC)
Solubility

Water: 4 mg/mL (13.59 mM); DMSO: 33 mg/mL (112.13 mM)
SMILES

O=C(O)C[C@H](N)C(N[C@@H](CC1=CC=CC=C1)C(OC)=O)=O
Chemical Name

(3S)-3-Amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid

1.Xu H, et al. Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14258-63.

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