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PF-06873600
CAS No. 2185857-97-8
PF-06873600( PF06873600 | PF 06873600 )
Catalog No. M13486 CAS No. 2185857-97-8
PF-06873600 (PF06873600, PF 06873600) is a potent, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 121 | In Stock |
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| 5MG | 117 | In Stock |
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| 10MG | 188 | In Stock |
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| 25MG | 353 | In Stock |
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| 50MG | 576 | In Stock |
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| 100MG | 918 | In Stock |
|
| 200MG | 1237 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePF-06873600
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NoteResearch use only, not for human use.
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Brief DescriptionPF-06873600 (PF06873600, PF 06873600) is a potent, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively.
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DescriptionPF-06873600 (PF06873600, PF 06873600) is a potent, orally bioavailable inhibitor of cyclin-dependent kinase (CDK) with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively; demonstrates potential antineoplastic activity, incerease apoptosis and inhibits umor cell proliferation.Breast Cancer Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsPF06873600 | PF 06873600
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PathwayCell Cycle/DNA Damage
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TargetCDK
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RecptorCDK
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Research AreaCancer
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IndicationBreast Cancer
Chemical Information
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CAS Number2185857-97-8
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Formula Weight471.524
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Molecular FormulaC20H27F2N5O4S
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Purity>98% (HPLC)
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SolubilityDMSO : 83.33 mg/mL 176.73 mM
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SMILESO=C1C(C(F)F)=CC2=CN=C(NC3CCN(S(=O)(C)=O)CC3)N=C2N1[C@H]4[C@](C)(O)CCC4
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Chemical NamePyrido[2,3-d]pyrimidin-7(8H)-one, 6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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