SC-806

CAS No. 216505-89-4

SC-806( SC 806 | SC806 )

Catalog No. M13454 CAS No. 216505-89-4

A potent, orally active p38 MAPK inhibitor with IC50 of 50 nM.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    SC-806
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, orally active p38 MAPK inhibitor with IC50 of 50 nM.
  • Description
    A potent, orally active p38 MAPK inhibitor with IC50 of 50 nM, significantly decreases incidence of arthritis in mouse collagen-induced arthritis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SC 806 | SC806
  • Pathway
    MAPK/ERK Signaling
  • Target
    p38 MAPK
  • Recptor
    p38 MAPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    216505-89-4
  • Formula Weight
    353.854
  • Molecular Formula
    C19H20ClN5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    1-(5-(4-chlorophenyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl)-4-methylpiperazine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Graneto MJ, et al. J Med Chem. 2007 Nov 15;50(23):5712-9.
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