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Stafib-2
CAS No. 2097938-74-2
Stafib-2( Stafib 2 )
Catalog No. M13314 CAS No. 2097938-74-2
Stafib-2 (Stafib 2) is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 596 | Get Quote |
|
| 10MG | 848 | Get Quote |
|
| 25MG | 1251 | Get Quote |
|
| 50MG | 1692 | Get Quote |
|
| 100MG | 2304 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameStafib-2
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NoteResearch use only, not for human use.
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Brief DescriptionStafib-2 (Stafib 2) is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.
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DescriptionStafib-2 (Stafib 2) is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.
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In VitroStafib-2 has an extremely high affinity for STAT5b (Ki=8.8 nM).Stafib-2 (3-10 μM; 4-48 h) does not show significant activity in K562 and MDA-MB-231 cells.
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In Vivo——
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SynonymsStafib 2
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number2097938-74-2
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Formula Weight644.466
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Molecular FormulaC28H26N2O12P2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (77.58 mM)
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SMILES——
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Chemical Name4-((2-(4-((4-phenoxyphenyl)carbamoyl)phenoxy)acetamido)methyl)-1,2-phenylene bis(dihydrogen phosphate)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Elumalai N, et al. Sci Rep. 2017 Apr 11;7(1):819.
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