Cart
sales@molnova.com
Home - Products - JAK/STAT Signaling - STAT - Stafib-2

Stafib-2

CAS No. 2097938-74-2

Stafib-2( Stafib 2 )

Catalog No. M13314 CAS No. 2097938-74-2

Stafib-2 (Stafib 2) is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 736 In Stock
5MG 519 In Stock
10MG 739 In Stock
25MG 1093 In Stock
50MG 1442 In Stock
100MG 1972 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Stafib-2
  • Note
    Research use only, not for human use.
  • Brief Description
    Stafib-2 (Stafib 2) is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.
  • Description
    Stafib-2 (Stafib 2) is a potent, selective small molecule inhibitor of transcription factor STAT5b with Ki of 9 nM, >20-fold selectivity over STAT5a.
  • In Vitro
    Stafib-2 has an extremely high affinity for STAT5b (Ki=8.8 nM).Stafib-2 (3-10 μM; 4-48 h) does not show significant activity in K562 and MDA-MB-231 cells.
  • In Vivo
    ——
  • Synonyms
    Stafib 2
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2097938-74-2
  • Formula Weight
    644.466
  • Molecular Formula
    C28H26N2O12P2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (77.58 mM)
  • SMILES
    ——
  • Chemical Name
    4-((2-(4-((4-phenoxyphenyl)carbamoyl)phenoxy)acetamido)methyl)-1,2-phenylene bis(dihydrogen phosphate)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Elumalai N, et al. Sci Rep. 2017 Apr 11;7(1):819.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Acetyl-trans-resvera...

    Acetyl-trans-resveratrol has anti-cancer activityit inhibits the phosphorylation of STAT3 and NFκB down-regulates Mcl-1 and up-regulates Bim and Puma in pancreatic cancer cells.

  • Nirsevimab

    Nirsevimab (MEDI8897) is a recombinant human respiratory syncytial virus (RSV) monoclonal antibody with a modified Fc region, efficiently targeting RSV-B with a Kd value of 1.5 nM, and can be used to prevent RSV infection.

  • IQDMA

    A cell-permeable, small molecule inhibitor of the transcription factor STAT5.

Sign In Join Free