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Finafloxacin

CAS No. 209342-40-5

Finafloxacin( —— )

Catalog No. M13289 CAS No. 209342-40-5

Finafloxacin is a fluoroquinolone antibiotic that demonstrates superior activity to ciprofloxacin under acidic conditions (pH5.8, A. baumannii isolates MIC=0.03-0.12ug/mL).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Finafloxacin
  • Note
    Research use only, not for human use.
  • Brief Description
    Finafloxacin is a fluoroquinolone antibiotic that demonstrates superior activity to ciprofloxacin under acidic conditions (pH5.8, A. baumannii isolates MIC=0.03-0.12ug/mL).
  • Description
    Finafloxacin is a fluoroquinolone antibiotic that demonstrates superior activity to ciprofloxacin under acidic conditions (pH5.8, A. baumannii isolates MIC=0.03-0.12ug/mL); shows comparable activity to ciprofloxacin at pH 7.2; Finafloxacin is a promising new antimicrobial agent for the treatment of A. baumannii infections at acidic body compartments.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    209342-40-5
  • Formula Weight
    398.3877
  • Molecular Formula
    C20H19FN4O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 6.4 mg/mL
  • SMILES
    C1CC1N2C=C(C(=O)C3=CC(=C(C(=C32)C#N)N4CC5C(C4)OCCN5)F)C(=O)O
  • Chemical Name
    3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Higgins PG, et al. Antimicrob Agents Chemother. 2010 Apr;54(4):1613-5. 2. Emrich NC, J Antimicrob Chemother. 2010 Dec;65(12):2530-3. 3. Dalhoff A, et al. Antimicrob Agents Chemother. 2011 Apr;55(4):1814-8.
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