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OSSK-674842
CAS No. 2054944-80-6
OSSK-674842( OSSK-2 | OSSK 674842 )
Catalog No. M13188 CAS No. 2054944-80-6
A novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameOSSK-674842
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NoteResearch use only, not for human use.
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Brief DescriptionA novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.
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DescriptionA novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.Cystic Fibrosis Preclinical.
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In Vitro——
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In Vivo——
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SynonymsOSSK-2 | OSSK 674842
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PathwayApoptosis
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TargetCFTR
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RecptorCFTR
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Research AreaOther Indications
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IndicationFibrosis
Chemical Information
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CAS Number2054944-80-6
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Formula Weight457.122
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Molecular FormulaC16H15Br2N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(N/N=C/C(C=C(Br)C(O)=C1Br)=C1O)CNC2=CC=C(C)C=C2
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Chemical Name(E)-N'-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(p-tolylamino)acetohydrazide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cui G, et al. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L192-207.
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