Cart
sales@molnova.com
OSSK-674842
CAS No. 2054944-80-6
OSSK-674842( OSSK-2 | OSSK 674842 )
Catalog No. M13188 CAS No. 2054944-80-6
A novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameOSSK-674842
-
NoteResearch use only, not for human use.
-
Brief DescriptionA novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.
-
DescriptionA novel potent CFTR potentiator that blocks hCFTR with apparent Kd of 71.3 uM; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.Cystic Fibrosis Preclinical.
-
In Vitro——
-
In Vivo——
-
SynonymsOSSK-2 | OSSK 674842
-
PathwayApoptosis
-
TargetCFTR
-
RecptorCFTR
-
Research AreaOther Indications
-
IndicationFibrosis
Chemical Information
-
CAS Number2054944-80-6
-
Formula Weight457.122
-
Molecular FormulaC16H15Br2N3O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(N/N=C/C(C=C(Br)C(O)=C1Br)=C1O)CNC2=CC=C(C)C=C2
-
Chemical Name(E)-N'-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-(p-tolylamino)acetohydrazide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Cui G, et al. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L192-207.
molnova catalog
related products
-
IOWH-032
A novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays for the treatment of cystic fibrosis; potentially serves as lead compound for development of new drugs for the treatment of cystic fibrosis.
-
UCCF-853
UCCF-853 is a small-molecule CFTR modulator that can be used to study cystic fibrosis.
-
FDL169
FDL-169 is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.
