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Marbostat-100
CAS No. 1876450-69-9
Marbostat-100( Marbostat 100 )
Catalog No. M12908 CAS No. 1876450-69-9
Marbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMarbostat-100
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NoteResearch use only, not for human use.
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Brief DescriptionMarbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM.
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DescriptionMarbostat-100 is a potent, selective HDAC6 inhibitor with Ki of 0.7 nM, displays >200-fold selectivity over HDAC1-5, and HDAC7-10; Marbostat-100 is a more selective HDAC6i than previously established well-characterized compounds; Marbostat-100 is well tolerated by mice and demonstrates in vivo anti-inflammatory activity against collagen type II induced arthritis, represents a most selective known HDAC6i and the possibility for clinical evaluation of a HDAC isoform-specific drug.
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In Vitro——
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In Vivo——
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SynonymsMarbostat 100
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research Area——
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Indication——
Chemical Information
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CAS Number1876450-69-9
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Formula Weight404.426
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Molecular FormulaC22H20N4O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-Hydroxy-4-((4-methyl-3,5-dioxo-3,4,5,6-tetrahydro-2,6-methano[1,3]diazocino[5,6-b]indol-11(1H)-yl)methyl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sellmer A, et al. J Med Chem. 2018 Apr 6. doi: 10.1021/acs.jmedchem.7b01593.
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