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Alflutinib
CAS No. 1869057-83-9
Alflutinib( AST2818 | AST-2818 | ASK120067 )
Catalog No. M12888 CAS No. 1869057-83-9
Alflutinib (AST-2818, ASK120067) is a third generation EGFR mutation selective tyrosine kinase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 155 | In Stock |
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| 5MG | 123 | In Stock |
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| 10MG | 187 | In Stock |
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| 25MG | 376 | In Stock |
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| 50MG | 554 | In Stock |
|
| 100MG | 731 | In Stock |
|
| 200MG | 1042 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAlflutinib
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NoteResearch use only, not for human use.
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Brief DescriptionAlflutinib (AST-2818, ASK120067) is a third generation EGFR mutation selective tyrosine kinase inhibitor.
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DescriptionAlflutinib (AST-2818, ASK120067) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.Lung Cancer Phase 1 Clinical.
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In VitroFirmonertinib is designed to inhibit EGFR active mutations as well as the T790M acquired resistant mutation.
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In Vivo——
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SynonymsAST2818 | AST-2818 | ASK120067
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR
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Research AreaCancer
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IndicationLung Cancer
Chemical Information
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CAS Number1869057-83-9
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Formula Weight568.605
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Molecular FormulaC28H31F3N8O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCN(C)CCN(C)c1nc(OCC(F)(F)F)c(Nc2nccc(n2)c3cn(C)c4ccccc34)cc1NC(=O)C=C
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Chemical NameN-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. PCT Int. Appl. (2017), WO 2017152707 A1 20170914.
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