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PD-150606
CAS No. 179528-45-1
PD-150606( PD 150606 | PD150606 )
Catalog No. M12710 CAS No. 179528-45-1
A potent and selective calpain inhibitor with Ki of 0.21 uM/0.37 uM for u-calpain/m-calpain, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 129 | In Stock |
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| 25MG | 270 | In Stock |
|
| 50MG | 482 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePD-150606
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NoteResearch use only, not for human use.
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Brief DescriptionA potent and selective calpain inhibitor with Ki of 0.21 uM/0.37 uM for u-calpain/m-calpain, respectively.
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DescriptionA potent and selective calpain inhibitor with Ki of 0.21 uM/0.37 uM for u-calpain/m-calpain, respectively; shows no inhibition for other proteases (cathepin B, papain, trypsin and thermolysin (Ki> 500 uM); attenuate shypoxic/hypoglycemic injury to cerebrocortical neurons in culture and excitotoxic injury to Purkinje cells in cerebellar slices.
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In Vitro——
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In Vivo——
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SynonymsPD 150606 | PD150606
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PathwayProteasome/Ubiquitin
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TargetProteasome
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RecptorProteasome
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number179528-45-1
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Formula Weight306.1201
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Molecular FormulaC9H7IO2S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 28 mg/mL
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SMILESO=C(O)/C(S)=C/C1=CC=C(I)C=C1
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Chemical Name2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto-, (2Z)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wang KK, et al. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6687-92.
2. Niapour M, et al. J Biol Chem. 2008 Aug 1;283(31):21371-81.
3. Waters SL, et al. J Pharmacol Exp Ther. 1997 Dec;283(3):1177-84.
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