Cart
sales@molnova.com
Revaprazan hydrochloride
CAS No. 178307-42-1
Revaprazan hydrochloride( SB-641257 | YH-1885 )
Catalog No. M12683 CAS No. 178307-42-1
Revaprazan (SB-641257;YH-1885) potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 33 | In Stock |
|
| 25MG | 67 | In Stock |
|
| 50MG | 104 | In Stock |
|
| 100MG | 163 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameRevaprazan hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionRevaprazan (SB-641257;YH-1885) potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner.
-
DescriptionRevaprazan (SB-641257;YH-1885) potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner; reduces gastric acid secretion, also exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling.Ulcer Approved.
-
In Vitro——
-
In Vivo——
-
SynonymsSB-641257 | YH-1885
-
PathwayMembrane Transporter/Ion Channel
-
TargetProton Pump
-
RecptorH+/K+-ATPase
-
Research AreaOther Indications
-
IndicationUlcer
Chemical Information
-
CAS Number178307-42-1
-
Formula Weight398.91
-
Molecular FormulaC22H24ClFN4
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESCl.CC1N(CCc2ccccc12)c3nc(Nc4ccc(F)cc4)nc(C)c3C
-
Chemical NameN-(4-fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)pyrimidin-2-amine hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Li H, et al. Drug Metab Dispos. 2001 Jan;29(1):54-9.
2. Lee JS, et al. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.
3. Inatomi N, et al. Pharmacol Ther. 2016 Dec;168:12-22.
molnova catalog
related products
-
Capmatinib 2HCl
INCB-28060(free base) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.
-
Levolansoprazole
Levolansoprazole, a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM).
-
Abeprazan hydrochlor...
Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activation.
