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NCX-4016
CAS No. 175033-36-0
NCX-4016( Nitroaspirin | NO-Aspirin )
Catalog No. M12651 CAS No. 175033-36-0
NCX-4016 (Nitroaspirin;NO-Aspirin 1) is a nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor, directly and irreversiblely inhibits COX-1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
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| 5MG | 71 | In Stock |
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| 10MG | 103 | In Stock |
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| 25MG | 174 | In Stock |
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| 50MG | 250 | In Stock |
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| 100MG | 367 | In Stock |
|
| 200MG | 547 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNCX-4016
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NoteResearch use only, not for human use.
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Brief DescriptionNCX-4016 (Nitroaspirin;NO-Aspirin 1) is a nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor, directly and irreversiblely inhibits COX-1.
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DescriptionNCX-4016 (Nitroaspirin;NO-Aspirin 1) is a nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor, directly and irreversiblely inhibits COX-1; suppresses platelet activation, platelet aggregation and thromboxane A2 production, reduces infarct size caused by myocardial ischemia-reperfusion in the anesthetized rat.Diabetes Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsNitroaspirin | NO-Aspirin
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX
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Research AreaMetabolic Disease
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IndicationDiabetes
Chemical Information
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CAS Number175033-36-0
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Formula Weight331.28
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Molecular FormulaC16H13NO7
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(OC1=CC=CC=C1CO[N+]([O-])=O)C2=CC=CC=C2OC(C)=O
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Chemical Name2-(Acetyloxy)-benzoic acid 3-[(nitrooxy)methyl]phenyl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Corazzi T, et al. J Pharmacol Exp Ther. 2005 Dec;315(3):1331-7.
2. Rossoni G, et al. J Pharmacol Exp Ther. 2001 Apr;297(1):380-7.
3. Lechi C, et al. Thromb Haemost. 1996 Nov;76(5):791-8.
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