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Home - Products - Chromatin/Epigenetic - COX - NCX-4016

NCX-4016

CAS No. 175033-36-0

NCX-4016( Nitroaspirin | NO-Aspirin )

Catalog No. M12651 CAS No. 175033-36-0

NCX-4016 (Nitroaspirin;NO-Aspirin 1) is a nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor, directly and irreversiblely inhibits COX-1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 51 In Stock
5MG 71 In Stock
10MG 103 In Stock
25MG 174 In Stock
50MG 250 In Stock
100MG 367 In Stock
200MG 547 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    NCX-4016
  • Note
    Research use only, not for human use.
  • Brief Description
    NCX-4016 (Nitroaspirin;NO-Aspirin 1) is a nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor, directly and irreversiblely inhibits COX-1.
  • Description
    NCX-4016 (Nitroaspirin;NO-Aspirin 1) is a nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor, directly and irreversiblely inhibits COX-1; suppresses platelet activation, platelet aggregation and thromboxane A2 production, reduces infarct size caused by myocardial ischemia-reperfusion in the anesthetized rat.Diabetes Phase 2 Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Nitroaspirin | NO-Aspirin
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX
  • Research Area
    Metabolic Disease
  • Indication
    Diabetes

Chemical Information

  • CAS Number
    175033-36-0
  • Formula Weight
    331.28
  • Molecular Formula
    C16H13NO7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(OC1=CC=CC=C1CO[N+]([O-])=O)C2=CC=CC=C2OC(C)=O
  • Chemical Name
    2-(Acetyloxy)-benzoic acid 3-[(nitrooxy)methyl]phenyl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Corazzi T, et al. J Pharmacol Exp Ther. 2005 Dec;315(3):1331-7. 2. Rossoni G, et al. J Pharmacol Exp Ther. 2001 Apr;297(1):380-7. 3. Lechi C, et al. Thromb Haemost. 1996 Nov;76(5):791-8.
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