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MMAD hydrochloride
CAS No. 173441-26-4
MMAD hydrochloride( Demethyldolastatin 10 hydrochloride | Monomethylauristatin D hydrochloride )
Catalog No. M12633 CAS No. 173441-26-4
A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMMAD hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionA potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).
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DescriptionA potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).
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In Vitro——
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In Vivo——
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SynonymsDemethyldolastatin 10 hydrochloride | Monomethylauristatin D hydrochloride
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PathwayAntibody Drug Conjugates (ADC)
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TargetADC Cytotoxin
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RecptorADC Cytotoxin
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number173441-26-4
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Formula Weight807.5253
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Molecular FormulaC41H67ClN6O6S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILES——
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Chemical NameL-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-, hydrochloride (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chudasama V, et al. Nat Chem. 2016 Feb;8(2):114-9.
2. Leal M, et al. Bioconjug Chem. 2015 Nov 18;26(11):2223-32.
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