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Selamectin (b)
CAS No. 165108-07-6
Selamectin (b)( —— )
Catalog No. M12522 CAS No. 165108-07-6
Selamectin is a topical parasiticide and antihelminthic used on dogs and cats, distributed by Zoetis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 106 | In Stock |
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| 10MG | 158 | In Stock |
|
| 25MG | 260 | In Stock |
|
| 50MG | 389 | In Stock |
|
| 100MG | 575 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSelamectin (b)
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NoteResearch use only, not for human use.
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Brief DescriptionSelamectin is a topical parasiticide and antihelminthic used on dogs and cats, distributed by Zoetis.
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DescriptionSelamectin is a topical parasiticide and antihelminthic used on dogs and cats, distributed by Zoetis. Selamectin disables parasites by activating glutamate-gated chloride channels at muscle synapses.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayNeuroscience
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TargetGluR
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RecptorGlutamate-gated chloride channels
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Research Area——
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Indication——
Chemical Information
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CAS Number165108-07-6
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Formula Weight769.96
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Molecular FormulaC43H63NO11
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Purity>98% (HPLC)
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SolubilitySoluble in Water
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SMILESC[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]\5[C@@]4([C@@H](C=C(/C5=N/O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)\C)O[C@@H]1C7CCCCC7
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Evans blue
Evans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT).
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Memantine hydrochlor...
Memantine is an uncompetitive NMDA receptor antagonist. When using HEK293 cells express recombinant rat NMDA receptors, memantine shows inhibition of L-glutamate-mediated response with a dose- and voltage-dependent manner.
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Basimglurant
Basimglurant is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM). In competition binding experiments on human recombinant mGlu5, Basimglurant (RG7090) fully displaces [3H]-MPEP with a Ki of 35.6 nM and [3H]-ABP688 with a Ki of 1.4 nM. In HEK293 cells stably expressing human mGlu5, Basimglurant (RG7090) inhibits quisqualate induced Ca2+ mobilization with an IC50 of 7.0 nM and [3H]-inositolphosphate accumulation (IC50 of 5.9 nM).
