Home - Products - GPCR/G Protein - Antibacterial - NITD-564

NITD-564

CAS No. 1614262-75-7

NITD-564( NITD564 )

Catalog No. M12348 CAS No. 1614262-75-7

NITD-564 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.59 uM, exhibits MIC50 of 160 nM against Mtb.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
100MG	Get Quote	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

NITD-564
Note

Research use only, not for human use.
Brief Description

NITD-564 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.59 uM, exhibits MIC50 of 160 nM against Mtb.
Description

NITD-564 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.59 uM, exhibits MIC50 of 160 nM against Mtb; binds specifically to InhA in an NADH-dependent manner and blocks the enoyl substrate-binding pocket; shows in vivo efficacy in acute and established mouse models of Mycobacterium tuberculosis infection.
In Vitro

——
In Vivo

——
Synonyms

NITD564
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

1614262-75-7
Formula Weight

283.371
Molecular Formula

C18H21NO2
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

6-(cyclohexylmethyl)-4-hydroxy-3-phenylpyridin-2(1H)-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Manjunatha UH, et al. Sci Transl Med. 2015 Jan 7;7(269):269ra3.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Nacubactam

Nacubactam is a potent inhibitor of non-β-lactam-β-lactamase with activity against class A and class C β-lactamases.
Allergen Gal d 4 (46...

Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.
PBP 10

Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.

Sign In Join Free