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HIF1-IN-2
CAS No. 159915-87-4
HIF1-IN-2( —— )
Catalog No. M12293 CAS No. 159915-87-4
A potent, selective HIF-1 inhibitor with IC50 of 1.9 nM, with no signigicant inhibition on HSF and NF-κB.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameHIF1-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective HIF-1 inhibitor with IC50 of 1.9 nM, with no signigicant inhibition on HSF and NF-κB.
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DescriptionA potent, selective HIF-1 inhibitor with IC50 of 1.9 nM, with no signigicant inhibition on HSF and NF-κB; robustly induces PGK1 and Enolase 1 expression, also inhibit endogenous HIF-1 targets.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetHIF/HIF Prolyl-hydroxylase
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RecptorHIF/HIF Prolyl-hydroxylase
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Research Area——
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Indication——
Chemical Information
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CAS Number159915-87-4
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Formula Weight453.583
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Molecular FormulaC26H35N3O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(Z)-2-(2-((4-((E)-1-(butoxyimino)propyl)-2,5-dimethylphenoxy)methyl)phenyl)-2-(methoxyimino)-N-methylacetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lin X, et al. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):174-9.
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