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Daminozide
CAS No. 1596-84-5
Daminozide( Alar | Aminozide | B 995 | DIMG | DMASA | Kylar | SADH | Succinic Acid )
Catalog No. M12281 CAS No. 1596-84-5
Daminozide(DMASA; DIMG; B 995), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 44 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 39 | In Stock |
|
| 1G | 47 | In Stock |
|
Biological Information
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Product NameDaminozide
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NoteResearch use only, not for human use.
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Brief DescriptionDaminozide(DMASA; DIMG; B 995), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.
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DescriptionDaminozide(DMASA; DIMG; B 995), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.(In Vitro):Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested (IC50=127 μM for KDM3A, or greater against other demethylases).(In Vivo):Daminozide (200-20000 ppm) has teratogenic and genotoxic effects on model organism Drosophila melanogaster.
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In VitroDaminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested (IC50=127 μM for KDM3A, or greater against other demethylases).
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In VivoDaminozide (200-20000 ppm) has teratogenic and genotoxic effects on model organism Drosophila melanogaster.
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SynonymsAlar | Aminozide | B 995 | DIMG | DMASA | Kylar | SADH | Succinic Acid
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorKDM2/7 JmjC
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1596-84-5
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Formula Weight160.17
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Molecular FormulaC6H12N2O3
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Purity>98% (HPLC)
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SolubilitySoluble in DMSO
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SMILESOC(CCC(NN(C)C)=O)=O
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Chemical Name4-(2,2-dimethylhydrazinyl)-4-oxobutanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Reed DJ, Moore TC, Anderson JD. Science. 1965 Jun 11;148(3676):1469-71.
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