Cart
sales@molnova.com
Bizine
CAS No. 1591932-50-1
Bizine( —— )
Catalog No. M12274 CAS No. 1591932-50-1
Bizine is a phenelzine analog that inhibits LSD1 with Ki of 59 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameBizine
-
NoteResearch use only, not for human use.
-
Brief DescriptionBizine is a phenelzine analog that inhibits LSD1 with Ki of 59 nM.
-
DescriptionBizine is a phenelzine analog that inhibits LSD1 with Ki of 59 nM, displays 23-fold, 63-fold, and >100-fold selectivity for LSD-1 over MAOA, MAOB, and LSD2 respectively; induces bulk histone H3 lysine 4 dimethylation in LNCaP cancer cells (EC50=2 uM), and protects neurons exposed to oxidative stress at 0.5 uM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetHistone Demethylase
-
RecptorHistone Demethylase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1591932-50-1
-
Formula Weight297.402
-
Molecular FormulaC18H23N3O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC1=CC=C(C=C1)CCCC(=O)NC2=CC=C(C=C2)CCNN.Cl.Cl
-
Chemical NameN-[4-(2-hydrazinylethyl)phenyl]-benzenebutanamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Prusevich P, et al. ACS Chem Biol. 2014 Jun 20;9(6):1284-93.
molnova catalog
related products
-
3-pyridine toxoflavi...
3-pyridine toxoflavin is a potent KDM4C inhibitor, IC50=19nM.
-
LSD1-IN-7 benzenesul...
LSD1-IN-7 benzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.
-
NCD-38
NCD-38 is a novel potent, selective LSD1 inhibitor with IC50 of 0.59 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes.
