Cortodoxone( 11-Deoxycortisol | Cortexolone )

Catalog No. M12133 CAS No. 152-58-9

Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Cortodoxone
Note

Research use only, not for human use.
Brief Description

Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).
Description

Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone); exhibits corticosteroid binding characteristics, including DNA binding; 11-deoxycortisol is regulated by the hypothalamus-pituitary axis and responded to acute stress; impedes GABAergic neurotransmission and induces drug-resistant status epilepticus in mice.
In Vitro

——
In Vivo

——
Synonyms

11-Deoxycortisol | Cortexolone
Pathway

Endocrinology/Hormones
Target

GR
Recptor

GlucocorticoidReceptor
Research Area

Inflammation/Immunology
Indication

——

Chemical Information

CAS Number

152-58-9
Formula Weight

346.4605
Molecular Formula

C21H30O4
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 33 mg/mL
SMILES

CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C(=O)CO)O)C
Chemical Name

Pregn-4-ene-3,20-dione, 17,21-dihydroxy-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Close DA, et al. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13942-7. 2. Kaminski RM, et al. Neuropharmacology. 2011 Jun;60(7-8):1098-108. 3. Baker ME, et al. Steroids. 2011 Dec 11;76(13):1451-7.

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