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U-93631
CAS No. 152273-12-6
U-93631( U93631 | U 93631 )
Catalog No. M12126 CAS No. 152273-12-6
A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 58 | In Stock |
|
| 25MG | 115 | In Stock |
|
| 50MG | 178 | In Stock |
|
| 100MG | 332 | In Stock |
|
| 500MG | 782 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameU-93631
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NoteResearch use only, not for human use.
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Brief DescriptionA potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction.
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DescriptionA potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction; induce a rapid, time-dependent decay of GABA-induced whole-cell Cl- currents in recombinant GABAA receptors.
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In Vitro——
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In Vivo——
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SynonymsU93631 | U 93631
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PathwayMembrane Transporter/Ion Channel
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TargetGAT
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RecptorGABA
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number152273-12-6
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Formula Weight299.3676
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Molecular FormulaC17H21N3O2
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 34 mg/mL
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SMILESO=C(C1=C2N(C=N1)C3=C(C=CC=C3)NC2(C)C)OC(C)(C)C
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Chemical NameImidazo[1,5-a]quinoxaline-3-carboxylic acid, 4,5-dihydro-4,4-dimethyl-, 1,1-dimethylethyl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Dillon GH, et al. Mol Pharmacol. 1993 Oct;44(4):860-5.
2. Dillon GH, et al. J Pharmacol Exp Ther. 1995 Feb;272(2):597-603.
3. Dillon GH, et al. Br J Pharmacol. 1995 Jun;115(3):539-45.
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