Cart
sales@molnova.com
GJ103 sodium salt
CAS No. 1459687-96-7
GJ103 sodium salt( GJ 103 sodium salt | GJ-103 sodium salt )
Catalog No. M11982 CAS No. 1459687-96-7
A novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 38 | In Stock |
|
| 5MG | 70 | In Stock |
|
| 10MG | 113 | In Stock |
|
| 25MG | 230 | In Stock |
|
| 50MG | 398 | In Stock |
|
| 100MG | 433 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGJ103 sodium salt
-
NoteResearch use only, not for human use.
-
Brief DescriptionA novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene.
-
DescriptionA novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene; induces ATM kinase on both TGA and TAG stop codons and restores ATMpSer1981 autophosphorylation and SMC1pSer966 transphosphorylation in A-T cells.
-
In Vitro——
-
In Vivo——
-
SynonymsGJ 103 sodium salt | GJ-103 sodium salt
-
PathwayCell Cycle/DNA Damage
-
TargetATM/ATR
-
RecptorATM
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number1459687-96-7
-
Formula Weight364.35418928
-
Molecular FormulaC16H13N4NaO3S
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 34 mg/mL
-
SMILESCOC1=CC=CC(=C1)N2C(=NN=C2SCC(=O)[O-])C3=CC=CC=N3.[Na+]
-
Chemical NameAcetic acid, 2-[[4-(3-methoxyphenyl)-5-(2-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-, sodium salt (1:1)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Du L, et al. Mol Ther. 2013 Sep;21(9):1653-60.
molnova catalog
related products
-
VE822
VE-822 is an ATR inhibitor with IC50 of 19 nM in HT29 cells.
-
Ro 90-7501
Ro 90-7501 is an amyloid β42 (Aβ42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest.
-
AZD1390
AZD1390 (AZD-1390) is a novel potent, selective, orally available and CNS penetrant ATM inhibitor with IC50 of 0.78 nM.Brain Cancer,Phase 1 Clinical
