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GJ103 sodium salt
CAS No. 1459687-96-7
GJ103 sodium salt( GJ 103 sodium salt | GJ-103 sodium salt )
Catalog No. M11982 CAS No. 1459687-96-7
A novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
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| 5MG | 45 | In Stock |
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| 10MG | 72 | In Stock |
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| 25MG | 145 | In Stock |
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| 50MG | 246 | In Stock |
|
| 100MG | 269 | In Stock |
|
| 200MG | 392 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGJ103 sodium salt
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NoteResearch use only, not for human use.
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Brief DescriptionA novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene.
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DescriptionA novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene; induces ATM kinase on both TGA and TAG stop codons and restores ATMpSer1981 autophosphorylation and SMC1pSer966 transphosphorylation in A-T cells.
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In Vitro——
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In Vivo——
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SynonymsGJ 103 sodium salt | GJ-103 sodium salt
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PathwayCell Cycle/DNA Damage
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TargetATM/ATR
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RecptorATM
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number1459687-96-7
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Formula Weight364.35418928
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Molecular FormulaC16H13N4NaO3S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 34 mg/mL
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SMILESCOC1=CC=CC(=C1)N2C(=NN=C2SCC(=O)[O-])C3=CC=CC=N3.[Na+]
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Chemical NameAcetic acid, 2-[[4-(3-methoxyphenyl)-5-(2-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-, sodium salt (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Du L, et al. Mol Ther. 2013 Sep;21(9):1653-60.
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