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Tetomilast
CAS No. 145739-56-6
Tetomilast( OPC-6535 )
Catalog No. M11976 CAS No. 145739-56-6
Tetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameTetomilast
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NoteResearch use only, not for human use.
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Brief DescriptionTetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions.
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DescriptionTetomilast (OPC-6535) is a superoxide anion production inhibitor that inhibits PDE4 and proinflammatory functions of leukocytes including superoxide production and cytokine release; attenuates sepsis-induced acute lung injury.COPD Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsOPC-6535
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE
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Research AreaInflammation/Immunology
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IndicationCOPD
Chemical Information
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CAS Number145739-56-6
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Formula Weight370.42
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Molecular FormulaC19H18N2O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=NC(C2=CSC(C3=CC=C(OCC)C(OCC)=C3)=N2)=CC=C1)O
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Chemical Name6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Schreiber S, et al. Gastroenterology. 2007 Jan;132(1):76-86.
2. Bloomfield GL, et al. J Surg Res. 1997 Sep;72(1):70-7.
3. Ejiri S, et al. Transplant Proc. 2000 Mar;32(2):318-21.
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