Cart
sales@molnova.com
PROTAC-VHL-ligand
CAS No. 1448297-52-6
PROTAC-VHL-ligand( —— )
Catalog No. M11915 CAS No. 1448297-52-6
PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 53 | Get Quote |
|
| 10MG | 77 | Get Quote |
|
| 25MG | 125 | Get Quote |
|
| 50MG | 178 | Get Quote |
|
| 100MG | 295 | Get Quote |
|
| 500MG | 709 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePROTAC-VHL-ligand
-
NoteResearch use only, not for human use.
-
Brief DescriptionPROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
-
DescriptionPROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayPROTACs
-
TargetE3 Ligase Ligand
-
RecptorE3 Ligase Ligand
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number1448297-52-6
-
Formula Weight430.567
-
Molecular FormulaC22H30N4O3S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (232.26 mM)
-
SMILESCC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)N)O
-
Chemical NameL-Prolinamide,3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-,(4R)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Bondeson DP, et al. Nat Chem Biol. 2015 Aug;11(8):611-7.
molnova catalog
related products
-
Cereblon modulator 1
Cereblon modulator 1 is a cereblon (CRBN) E3 ligase modulator. It specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.
-
VH 298
A potent, specific cell-active VHL E3 ubiquitin ligase inhibitor that inhibits VHL/HIF-α interaction with Kd of 90 nM in ITC assays.
-
VHL-2
A VHL ligand for PROTAC.
