Adefovir dipivoxil( GS 840, GS-0840, Hepsera | Preveon. )

Catalog No. M11786 CAS No. 142340-99-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Adefovir dipivoxil
Note

Research use only, not for human use.
Brief Description

Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B.
Description

Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
In Vitro

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In Vivo

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Synonyms

GS 840, GS-0840, Hepsera | Preveon.
Pathway

Microbiology/Virology
Target

Other Targets
Recptor

Protein P| Reverse Transcriptase| Reverse Transcriptase
Research Area

Infection
Indication

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CAS Number

142340-99-6
Formula Weight

501.47
Molecular Formula

C20H32N5O8P
Purity

>98% (HPLC)
Solubility

Ethanol: 100 mg/mL (199.41 mM); DMSO: 100 mg/mL (199.41 mM)
SMILES

CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C
Chemical Name

[2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate